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Comparison of Abilities of Salmonella enterica Serovar Typhimurium aroA aroD and aroA htrA Mutants To Act as Live Vectors

机译：鼠伤寒沙门氏菌鼠伤寒杆菌aroA aroD和aroA htrA突变体作为活载体的能力比较

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We compared the ability of Salmonella enterica serovar Typhimurium SL1344 aroA aroD (BRD509) and aroA htrA (BRD807) mutants to act as live vectors for delivery of fragment C of tetanus toxin (FrgC). FrgC was expressed in these strains from either pTETnir15 or pTEThtrA1. BRD509FrgC+ strains elicited ∼2-log-higher serum anti-FrgC antibody titers than BRD807FrgC+ strains. All mice immunized with BRD807pTEThtrA1, BRD509pTEThtrA1, and BRD509pTETnir15 (but not BRD807pTETnir15) were protected against tetanus.

机译：我们比较了沙门氏菌血清型鼠伤寒沙门氏菌SL1344 aroA aroD（BRD509）和aroA htrA（BRD807）突变体作为活载体传递破伤风毒素（FrgC）片段C的能力。在来自pTETnir15或pTEThtrA1的这些菌株中表达了FrgC。与BRD807FrgC +菌株相比，BRD509FrgC +菌株的血清抗FrgC抗体滴度高约2个对数。 BRD807pTEThtrA1，BRD509pTEThtrA1和BRD509pTETnir15（而非BRD807pTETnir15）免疫的所有小鼠均免受破伤风的侵害。

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Roberts, Mark; Chatfield, Steven; Pickard, Derek; Li, Jingli; Bacon, Andrew;
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年度 2000
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1. Comparison of Abilities of Salmonella enterica Serovar Typhimurium aroA aroD and aroA htrA Mutants To Act as Live Vectors [J] . Mark Roberts, Steven Chatfield, Derek Pickard, Infection and immunity . 2000,第10期

机译：鼠伤寒沙门氏菌鼠伤寒杆菌aroA aroD和aroA htrA突变体作为活载体的能力比较
2. Comparison of Abilities of Salmonella enterica Serovar Typhimurium aroA aroD and aroA htrA Mutants To Act as Live Vectors [J] . Mark Roberts, Steven Chatfield, Derek Pickard, Infection and immunity . 2000,第10期

机译：鼠伤寒沙门氏菌鼠伤寒杆菌aroA aroD和aroA htrA突变体作为活载体的能力比较
3. Salmonella typhimurium aroA, htrA, and aroD htrA mutants cause progressive infections in athymic (nuu) BALB/c mice. [J] . K Sinha, P Mastroeni, J Harrison, Infection and immunity . 1997,第4期

机译：鼠伤寒沙门氏菌aroA，htrA和aroD htrA突变体在无胸腺（nu / nu）BALB / c小鼠中引起进行性感染。
4. A comparison of sampling methods for Salmonella enterica serovar Typhimurium [C] . Will Fombelle, Carrie Pollard, Noel Garbes, Annual^Meeting of the American Association^of^Swine^Veterinarians. . 2014

机译：Salmonella肠道血吸虫伤寒沙门氏菌采样方法的比较
5. Comparison of the genetics and in-vitro virulence of Salmonella enterica serovar Typhimurium isolated from California dairy cattle and humans. [D] . Adaska, John Michael. 2005

机译：从加利福尼亚奶牛和人类分离的肠炎沙门氏菌鼠伤寒沙门氏菌的遗传学和体外毒力比较。
6. Note: Comparison of Abilities of Salmonella enterica Serovar Typhimurium aroA aroD and aroA htrA Mutants To Act as Live Vectors [O] . Mark Roberts, Steven Chatfield, Derek Pickard, 2000

机译：注意：沙门氏菌鼠伤寒沙门氏菌aroA aroD和aroa htrA突变体作为活载体的能力比较
7. Salmonella typhimurium aroA, htrA, and aroD htrA mutants cause progressive infections in athymic (nu/nu) BALB/c mice [O] . K Sinha, P Mastroeni, J Harrison, 1997

机译：沙门氏菌伤寒术aroa，htra和arod htra突变体导致胸肉（nu / nu）balb / c小鼠进行渐进式感染

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Comparison of Abilities of Salmonella enterica Serovar Typhimurium aroA aroD and aroA htrA Mutants To Act as Live Vectors

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